Physician vs. CAD Agreement: Concordance improved from 47.3% to 76.1% over nine months.
Published 29 Oct 2023
Computer-Aided Detection for Chest Radiography to Improve the Quality of Tuberculosis Diagnosis in Vietnam's District Health Facilities: An Implementation Study
Author: Anh L. Innes,
Andres Martinez,
Xiaoming Gao,
Nhi Dinh,
Gia Linh Hoang,
Thi Bich Phuong Nguyen,
Viet Hien Vu,
Tuan Ho Thanh Luu,
Thi Thu Trang Le,
Victoria Lebrun,
Van Chinh Trieu,
Nghi Do Bao Tran,
Zhi Zhen Qin,
Huy Minh Pham,
Van Luong Dinh,
Binh Hoa Nguyen,
Thi Thanh Huyen Truong,
Van Cu Nguyen,
Viet Nhung Nguyen,
Thu Hien Mai
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Xpert Referrals: Increased from 7.8% to 9.6%.
TB Detection Yield: Xpert-confirmed TB cases per 100,000 CXRs rose from 858 to 2112.
TB Detection: Physicians flagged 9.1% of CXRs as TB-presumptive, while CAD flagged 14.6%.
Xpert Positivity Rate: CAD + physician-flagged CXRs had a higher positivity rate (28.9%) vs. overall (19.3%).
Conclusion:
AI-assisted qXR 3.0 improved TB detection, increased physician-CAD agreement, and optimized Xpert testing referrals. CAD-supported screening enhanced case detection, making it a valuable tool for public health. Further threshold calibration is needed to refine sensitivity and specificity. Integration of qXR AI into TB screening can improve diagnostics in high-burden, low-resource settings.
Authors
Anh L. Innes, Andres Martinez, Xiaoming Gao, Nhi Dinh, Gia Linh Hoang, Thi Bich Phuong Nguyen, Viet Hien Vu, Tuan Ho Thanh Luu, Thi Thu Trang Le, Victoria Lebrun, Van Chinh Trieu, Nghi Do Bao Tran, Zhi Zhen Qin, Huy Minh Pham, Van Luong Dinh, Binh Hoa Nguyen, Thi Thanh Huyen Truong, Van Cu Nguyen, Viet Nhung Nguyen, Thu Hien Mai
