This is a systematic literature review of cost-of-illness studies on heart failure-related costs in the USA from January 2014 to March 2020.
Sample Size:
The study included 87 cost-of-illness studies, with 41 studies allowing direct cost comparisons.
Summary:
This systematic review assessed heart failure-related healthcare costs in the USA, revealing that the median annual total medical cost per patient was $24,383, with hospitalizations being the primary cost driver (median $15,879 per patient). Costs varied significantly based on patient characteristics such as comorbidities and age, highlighting the need for cost differentiation by heart failure type (e.g., higher costs for heart failure with reduced ejection fraction compared to preserved ejection fraction). The review also identified challenges in standardizing cost estimates due to differences in study design and reporting methods. The findings reinforce that hospitalization remains the key cost driver, and a better understanding of cost variations is crucial for economic evaluations of new heart failure treatments.
Sample Size:
The study included 87 cost-of-illness studies, with 41 studies allowing direct cost comparisons.
Summary:
This systematic review assessed heart failure-related healthcare costs in the USA, revealing that the median annual total medical cost per patient was $24,383, with hospitalizations being the primary cost driver (median $15,879 per patient). Costs varied significantly based on patient characteristics such as comorbidities and age, highlighting the need for cost differentiation by heart failure type (e.g., higher costs for heart failure with reduced ejection fraction compared to preserved ejection fraction). The review also identified challenges in standardizing cost estimates due to differences in study design and reporting methods. The findings reinforce that hospitalization remains the key cost driver, and a better understanding of cost variations is crucial for economic evaluations of new heart failure treatments.
